1. Fetoplacental vascular endothelial dysfunction as an early phenomenon in the programming of human adult diseases in subjects born from gestational diabetes mellitus or obesity in pregnancy.
Leiva A , Pardo F , Ramírez MA , Farías M , Casanello P , Sobrevia L .
Exp Diabetes Res. 2011;2011:349286.
2. Functional link between adenosine and insulin: a hypothesis for fetoplacental vascular endothelial dysfunction in gestational diabetes.
Guzmán-Gutiérrez E, Abarzúa F, Belmar C, Nien JK, Ramírez MA, Arroyo P, Salomón C, Westermeier F, Puebla C, Leiva A, Casanello P, Sobrevia L .
Curr Vasc Pharmacol . 2011 Nov;9(6):750-62.
3. Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium.
Prieto CP, Krause BJ, Quezada C, San Martin R, Sobrevia L , Casanello P.
Placenta . 2011 Dec;32(12):932-40. Epub 2011 Oct 1.
4. Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium.
Westermeier F, Salomón C, González M, Puebla C, Guzmán-Gutiérrez E, Cifuentes F, Leiva A, Casanello P, Sobrevia L .
Diabetes . 2011 Jun;60(6):1677-87. Epub 2011 Apr 22.
5. Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium.
Westermeier F, Salomón C, González M, Puebla C, Guzmán-Gutiérrez E, Cifuentes F, Leiva A, Casanello P, Sobrevia L .
Diabetes . 2011 Jun;60(6):1677-87. Epub 2011 Apr 22.
6. Increased expression of the multidrug resistance-associated protein 1 (MRP1) in kidney glomeruli of streptozotocin-induced diabetic rats.
Quezada C, Alarcón S, Cárcamo JG, Yáñez A, Casanello P, Sobrevia L , San Martín R.
Biol Chem . 2011 Apr;392(6):529-37. Epub 2011 Apr 17.
7. Placenta. Trophoblast Research. Preface.
Sobrevia L .
Placenta . 2011 Mar;32 Suppl 2:S78-80. No abstract available.
8.Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation.
González M, Gallardo V, Rodríguez N, Salomón C, Westermeier F, Guzmán-Gutiérrez E, Abarzúa F, Leiva A, Casanello P, Sobrevia L .
J Cell Physiol . 2011 Nov;226(11):2916-24. doi: 10.1002/jcp.22635.
9. Review: Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes.
Sobrevia L , Abarzúa F, Nien JK, Salomón C, Westermeier F, Puebla C, Cifuentes F, Guzmán-Gutiérrez E, Leiva A, Casanello P.
Placenta . 2011 Mar;32 Suppl 2:S159-64. Epub 2011 Jan 6. Review.
10. The activity of the multidrug resistance-associated protein 1 (MRP1) is increased in kidney glomeruli of diabetic rats.
Quezada C, Alarcón S, Cárcamo JG, Yáñez A, Casanello P, Sobrevia L , San Martín R.
Biological Chemistry, 2011. (In Press).
11. Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes.
Sobrevia L , Abarzúa F, Nien JK, Salomón C, Westermeier W, Puebla C, Cifuentes F, Guzmán-Gutiérrez E, Leiva A, Casanello P.
Placenta 2011, doi:10.1016/j.placenta.2010.12.011
12. Preface.
Sobrevia L.
Placenta. 2011, doi:10.1016/j.placenta.2010.11.015
13. Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells.
Guzmán-Gutiérrez E, Sandoval C, Nova E, Castillo JL, Vera JC, Lamperti L, Krause B, Salomón C, Sepúlveda C, Aguayo C, Sobrevia L .
Placenta . 2010, 31:928-936
14. IFPA Meeting 2009 workshops report.
Lash GE, Burton GJ, Chamley LW, Clifton VL, Constancia M, Crocker IP, Dantzer V, Desoye G, Drewlo S, Hemmings DG, Hiendleder S, Kalionis B, Keelan JA, Kudo Y, Lewis RM, Manuelpillai U, Murthi P, Natale D, Pfarrer C, Robertson S, Saffery R, Saito S, Sferruzzi-Perri A, Sobrevia L, Waddell BJ, Roberts CT.
Placenta . 2010 Mar;31 Suppl:S4-20. Epub 2010 Jan 12. PMID: 20064659 [PubMed - in process] Related citations
15. Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBPalpha in human umbilical vein endothelial cells from gestational diabetes.
Farías M, Puebla C, Westermeier F, Jo MJ, Pastor-Anglada M, Casanello P, Sobrevia L.
Cardiovasc Res . 2010 Apr 1;86(1):45-54. Epub 2009 Dec 23. PMID: 20032083 [PubMed - in process] Related citations
16. Control of the vasculature: pharmacological targets in vascular disease.
Sobrevia L.
Curr Vasc Pharmacol . 2009 Oct;7(4):423-5. No abstract available. PMID: 19863478 [PubMed - indexed for MEDLINE] Related citations
17. Adenosine mediates transforming growth factor-beta 1 release in kidney glomeruli of diabetic rats.
Roa H, Gajardo C, Troncoso E, Fuentealba V, Escudero C, Yáñez A, Sobrevia L, Pastor-Anglada M, Quezada C, San Martin R.
FEBS Lett . 2009 Oct 6;583(19):3192-8. Epub 2009 Sep 6. PMID: 19737558 [PubMed - indexed for MEDLINE] Related citations
18. Reduced l-arginine transport and nitric oxide synthesis in human umbilical vein endothelial cells from intrauterine growth restriction pregnancies is not further altered by hypoxia.
Casanello P, Krause B, Torres E, Gallardo V, González M, Prieto C, Escudero C, Farías M, Sobrevia L.
Placenta . 2009 Jul;30(7):625-33. Epub 2009 Jun 7. PMID: 19501907 [PubMed - indexed for MEDLINE] Related citations
19. Potential cell signalling mechanisms involved in differential placental angiogenesis in mild and severe pre-eclampsia.
Escudero C, Puebla C, Westermeier F, Sobrevia L.
Curr Vasc Pharmacol . 2009 Oct;7(4):475-85. Review. PMID: 19485894 [PubMed - indexed for MEDLINE] Related citations
20. A role for insulin on L-arginine transport in fetal endothelial dysfunction in hyperglycaemia.
Sobrevia L, González M.
Curr Vasc Pharmacol . 2009 Oct;7(4):467-74. Review. PMID: 19485892 [PubMed - indexed for MEDLINE] Related citations
21. Epigenetics: new concepts of old phenomena in vascular physiology.
Krause B, Sobrevia L, Casanello P.
Curr Vasc Pharmacol . 2009 Oct;7(4):513-20. Review. PMID: 19485890 [PubMed - indexed for MEDLINE] Related citations
22. Do adenosine receptors offer new therapeutic options for diabetic nephropathy?
San Martín R, Valladares D, Roa H, Troncoso E, Sobrevia L.
Curr Vasc Pharmacol . 2009 Oct;7(4):450-9. Review. PMID: 19485887 [PubMed - indexed for MEDLINE] Related citations
23. Equilibrative nucleoside transporters in fetal endothelial dysfunction in diabetes mellitus and hyperglycaemia.
Westermeier F, Puebla C, Vega JL, Farías M, Escudero C, Casanello P, Sobrevia L.
Curr Vasc Pharmacol . 2009 Oct;7(4):435-49. Review. PMID: 19485884 [PubMed - indexed for MEDLINE] Related citations
24. TGF-beta1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium.
Vega JL, Puebla C, Vásquez R, Farías M, Alarcón J, Pastor-Anglada M, Krause B, Casanello P, Sobrevia L.
Cardiovasc Res . 2009 Jun 1;82(3):458-67. Epub 2009 Feb 4. PMID: 19193655 [PubMed - indexed for MEDLINE] Related citations
25. Brain natriuretic peptide (BNP) produced by the human chorioamnion may mediate pregnancy myometrial quiescence.
Carvajal JA, Delpiano AM, Cuello MA, Poblete JA, Casanello PC, Sobrevia LA, Weiner CP.
Reprod Sci . 2009 Jan;16(1):32-42. PMID: 19144889 [PubMed - indexed for MEDLINE] Related citations
26. Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A2B adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia.
Escudero C, Casanello P, Sobrevia L.
Placenta . 2008 Sep;29(9):816-25. Epub 2008 Aug 13. PMID: 18703227 [PubMed - indexed for MEDLINE] Related citations
27. A hypothesis for preeclampsia: adenosine and inducible nitric oxide synthase in human placental microvascular endothelium.
Escudero C, Sobrevia L.
Placenta . 2008 Jun;29(6):469-83. Epub 2008 Mar 24. Review. PMID: 18359514 [PubMed - indexed for MEDLINE] Related citations
28. High D-glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium.
Puebla C, Farías M, González M, Vecchiola A, Aguayo C, Krause B, Pastor-Anglada M, Casanello P, Sobrevia L.
J Cell Physiol . 2008 Jun;215(3):645-56. PMID: 18064606 [PubMed - indexed for MEDLINE] Related citations
29. Adenosine A(2B) receptor mediates an increase on VEGF-A production in rat kidney glomeruli.
Valladares D, Quezada C, Montecinos P, Concha II, Yañez AJ, Sobrevia L, San Martín R.
Biochem Biophys Res Commun . 2008 Feb 1;366(1):180-5. Epub 2007 Dec 3. PMID: 18060864 [PubMed - indexed for MEDLINE] Related citations
30. D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium.
Vásquez R, Farías M, Vega JL, Martin RS, Vecchiola A, Casanello P, Sobrevia L.
J Cell Physiol . 2007 Sep;212(3):626-32. PMID: 17427197 [PubMed - indexed for MEDLINE] Related citations
31. Equilibrative nucleoside (ENTs) and cationic amino acid (CATs) transporters: implications in foetal endothelial dysfunction in human pregnancy diseases.
Casanello P, Escudero C, Sobrevia L.
Curr Vasc Pharmacol . 2007 Jan;5(1):69-84. Review. PMID: 17266615 [PubMed - indexed for MEDLINE] Related citations
32. Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium.
Muñoz G, San Martín R, Farías M, Cea L, Vecchiola A, Casanello P, Sobrevia L.
J Cell Physiol . 2006 Dec;209(3):826-35. PMID: 16924660 [PubMed - indexed for MEDLINE] Related citations
33. Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endothelium from gestational diabetes.
Farías M, San Martín R, Puebla C, Pearson JD, Casado JF, Pastor-Anglada M, Casanello P, Sobrevia L.
J Cell Physiol . 2006 Aug;208(2):451-60. PMID: 16688763 [PubMed - indexed for MEDLINE] Related citations
34. Gestational diabetes and the adenosine/L-arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium.
San Martín R, Sobrevia L.
Placenta . 2006 Jan;27(1):1-10. Review. PMID: 16310032 [PubMed - indexed for MEDLINE] Related citations
35. Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia.
Aguayo C, Casado J, González M, Pearson JD, Martín RS, Casanello P, Pastor-Anglada M, Sobrevia L.
Placenta . 2005 Sep-Oct;26(8-9):641-53. Epub 2004 Dec 15. PMID: 16085043 [PubMed - indexed for MEDLINE] Related citations
36. Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium.
Casanello P, Torres A, Sanhueza F, González M, Farías M, Gallardo V, Pastor-Anglada M, San Martín R, Sobrevia L.
Circ Res . 2005 Jul 8;97(1):16-24. Epub 2005 Jun 2. PMID: 15933265 [PubMed - indexed for MEDLINE] Free Article Related citations
37. Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium.
Vásquez G, Sanhueza F, Vásquez R, González M, San Martín R, Casanello P, Sobrevia L.
J Physiol . 2004 Oct 1;560(Pt 1):111-22. Epub 2004 Jul 22. PMID: 15272035 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
38. Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells.
González M, Flores C, Pearson JD, Casanello P, Sobrevia L.
Pflugers Arch . 2004 Jul;448(4):383-94. Epub 2004 Apr 3. PMID: 15064952 [PubMed - indexed for MEDLINE] Related citations
39. Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y+L in human umbilical vein endothelium.
Arancibia-Garavilla Y, Toledo F, Casanello P, Sobrevia L.
Exp Physiol . 2003 Nov;88(6):699-710. PMID: 14603368 [PubMed - indexed for MEDLINE] Free Article Related citations
40. Hyperglycaemia inhibits thymidine incorporation and cell growth via protein kinase C, mitogen-activated protein kinases and nitric oxide in human umbilical vein endothelium.
Rojas S, Rojas R, Lamperti L, Casanello P, Sobrevia L.
Exp Physiol . 2003 Mar;88(2):209-19. PMID: 12621526 [PubMed - indexed for MEDLINE] Free Article Related citations
41. Rapid stimulation of L-arginine transport by D-glucose involves p42/44(mapk) and nitric oxide in human umbilical vein endothelium.
Flores C, Rojas S, Aguayo C, Parodi J, Mann G, Pearson JD, Casanello P, Sobrevia L.
Circ Res . 2003 Jan 10;92(1):64-72. PMID: 12522122 [PubMed - indexed for MEDLINE] Free Article Related citations
42. Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells.
Mann GE, Yudilevich DL, Sobrevia L.
Physiol Rev . 2003 Jan;83(1):183-252. Review. PMID: 12506130 [PubMed - indexed for MEDLINE] Free Article Related citations
43. Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
Wyatt AW, Steinert JR, Wheeler-Jones CP, Morgan AJ, Sugden D, Pearson JD, Sobrevia L, Mann GE.
FASEB J . 2002 Oct;16(12):1584-94. PMID: 12374781 [PubMed - indexed for MEDLINE] Free Article Related citations
44. Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y+/hCAT-1 and y+/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells.
Casanello P, Sobrevia L.
Circ Res . 2002 Jul 26;91(2):127-34. PMID: 12142345 [PubMed - indexed for MEDLINE] Free Article Related citations
45. Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P2Y2 purinoceptors in human umbilical vein endothelial cells.
Parodi J, Flores C, Aguayo C, Rudolph MI, Casanello P, Sobrevia L.
Circ Res . 2002 Mar 22;90(5):570-7. PMID: 11909821 [PubMed - indexed for MEDLINE] Free Article Related citations
46. Modulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnancies.
Aguayo C, Flores C, Parodi J, Rojas R, Mann GE, Pearson JD, Sobrevia L.
J Physiol . 2001 Jul 1;534(Pt 1):243-54. PMID: 11433005 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
47. Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase.
Montecinos VP, Aguayo C, Flores C, Wyatt AW, Pearson JD, Mann GE, Sobrevia L.
J Physiol . 2000 Dec 15; 529 Pt 3:777-90. PMID: 11118505 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
48. [Tumorogenesis and mdm2 protein]
Flores C, Sobrevia L.
Rev Med Chil . 2000 May;128(5):539-46. Review. Spanish. PMID: 11008360 [PubMed - indexed for MEDLINE] Related citations
49. Nitric oxide, cGMP and cAMP modulate nitrobenzylthioinosine-sensitive adenosine transport in human umbilical artery smooth muscle cells from subjects with gestational diabetes.
Aguayo C, Sobrevia L.
Exp Physiol . 2000 Jul;85(4):399-409. PMID: 10918079 [PubMed - indexed for MEDLINE] Free Article Related citations
50. Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies.
Sobrevia L, Yudilevich DL, Mann GE.
J Physiol . 1998 Jan 1;506 ( Pt 1):219-30. PMID: 9481683 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
51. Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia.
Sobrevia L, Mann GE.
Exp Physiol . 1997 May;82(3):423-52. Review. PMID: 9179565 [PubMed - indexed for MEDLINE] Free Article Related citations
52. Activation of A2-purinoceptors by adenosine stimulates L-arginine transport (system y+) and nitric oxide synthesis in human fetal endothelial cells.
Sobrevia L, Yudilevich DL, Mann GE.
J Physiol . 1997 Feb 15;499 ( Pt 1):135-40. PMID: 9061645 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
53. Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
Contreras R, Fuentes O, Mann GE, Sobrevia L.
J Physiol . 1997 Feb 1;498 ( Pt 3):787-96. PMID: 9051589 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
54. Bovine adrenal endothelial cells express nucleoside transporters nonregulated by protein kinases A and C.
Sen RP, Sobrevía L, Delicado EG, Yudilevich D, Miras-Portugal MT.
Am J Physiol . 1996 Aug;271( 2 Pt 1):C504-10. PMID: 8769989 [PubMed - indexed for MEDLINE] Related citations
55. Activation of L-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells.
Sobrevia L, Nadal A, Yudilevich DL, Mann GE.
J Physiol . 1996 Feb 1;490 ( Pt 3):775-81. PMID: 8683475 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
56. Diabetes-induced activation of system y+ and nitric oxide synthase in human endothelial cells: association with membrane hyperpolarization.
Sobrevia L, Cesare P, Yudilevich DL, Mann GE.
J Physiol . 1995 Nov 15;489 ( Pt 1):183-92. PMID: 8583401 [PubMed - indexed for MEDLINE] Free PMC Article Free text Related citations
57. Transport and metabolism of adenosine in diabetic human placenta.
Osses N, Sobrevia L, Cordova C, Jarvis SM, Yudilevich DL.
Reprod Fertil Dev . 1995;7(6):1499-503. PMID: 8743154 [PubMed - indexed for MEDLINE] Related citations
58. Adenosine transport in cultured human umbilical vein endothelial cells is reduced in diabetes.
Sobrevía L, Jarvis SM, Yudilevich DL.
Am J Physiol . 1994 Jul;267( 1 Pt 1):C39-47. PMID: 8048491 [PubMed - indexed for MEDLINE] Related citations
59. Uptake of L-leucine and L-phenylalanine across the basolateral cell surface in isolated oxyntic glands.
Sobrevía L, Medina V, Reinicke K, Bravo I.
Biochim Biophys Acta . 1992 May 21;1106(2):257-63. PMID: 1596506 [PubMed - indexed for MEDLINE] Related citations
60. Kinetics and specificity of L-alanine transport across the basolateral cell surface in isolated oxyntic glands.
Bravo I, Sobrevía L.
Biochim Biophys Acta . 1990 Nov 2;1029(1):98-104. PMID: 2223817 [PubMed - indexed for MEDLINE] Related citations
